The Centurions, Cup winners at Wembley in 1971, established a 26-12 half-time lead at Leigh Sports Village, where Brierley, who is on loan from Castleford, provided the second-half highlight with a hat-trick.

Other former Wembley winners Sheffield Eagles ran in nine tries in a 50-12 rout of York at the Huntington Stadium.

Nev Morrison and Quentin Laulu-Togagae both scored two tries as the Eagles built on an 18-0 half-time advantage.

John Kear, a Cup winner with Sheffield and Hull, saw his Batley side hang on for a 21-18 victory at Hunslet.

Tries from Gareth Potts, Gareth Moore, Alex Walmsley and Ian Preece put Kear's men into a 20-10 lead early in the second half, but Andrew Yates and David March both scored their second tries of the match to set up a tense finish.

With both teams scoring four tries, Moore's two goals to one from the Hawks' Luke Helliwell proved the difference while the Batley half-back also put over a 78th-minute drop goal.

Oldham over-turned a 14-6 half-time deficit to score 20 unanswered points after the break and run out 26-14 winners over Barrow to book their place in Monday's fifth-round draw.